Health Clinics & DNA Tests

Wednesday, April 30th Lobby Office - All Star Expo Hall, Gettysburg PA

9:00-4:00pm: Cardiac, Eye, Thyroid or GenSol DNA questions: Dr. Samantha Judge, Health Clinic Chair, at [email protected]

9:00-1:00pm: Antagene Histiocytic Risk Test Clinic - Required Forms:

Memorandum of Agreement/Terms & Conditions (Only one Agreement required per owner/breeder participating in clinic)

Sampling Certificate

4 Generation Pedigree (download from the Berner-Garde database for each dog being tested https://bernergarde.org/DB/Default)

CLINIC & RISK TEST INFORMATION

Frequently Asked Questions (FAQ )

Home Instructions (for samples hand-delivered to the in-person clinic)

Overview of Antagene's HSIMS Mate Selection Tool

Direct all questions for the Histio Risk Clinic (or Liquid Biopsy study) not addressed in the Home Instructions or FAQ to Julie Jackson at [email protected]

IMPORTANT NOTE: The individual listed as "Owner" will receive results by email AND will be the only authorized user* for the tested dog on the HSIMS test mating website. If you prefer your Breeder/Co-Owner receive the results/breeder tool access, list that individual's name and email in the Comment section. *ONLY ONE USER PER DOG.

The ANTAGENE Laboratory, in collaboration with the CNRS Canine Genetics Team, has agreed to partner with the BMDCA to offer a clinic for the Histiocytic Sarcoma Risk Test at the BMDCA National Specialty. Normal price per dog is ~$120USD but BMDCA is pleased to announce special subsidized pricing for this clinic, with rates as low as $50! (See Options)

For over ten years, the Canine Genetics team of the CNRS in Rennes (France) and their international collaborators have been conducting genetic studies on Histiocytic Sarcoma in the Bernese Mountain Dog. These studies allowed them to locate regions of the genome implicated in this disease. The analysis of a large number of samples (more than 2000 Bernese Mountain Dogs) from affected dogs as well as old healthy dogs has enabled researchers to identify genetic markers associated with risk of developing and transmitting this cancer. Studies continue to investigate these genomic regions. Statistical analysis of these genetic markers has been used to produce a genetic index. This index can help breeders in the selection of breeding stock and matings. It is not, however, a prediction of the occurrence of the disease. This test is only a probability test, based on information from a population of 2,000 French Bernese Mountain Dogs; validated on European and American populations (over 900 Bernese Mountain Dogs in the U.S.)

The test for Histiocytic Sarcoma is not an endpoint but a continuation of the research on Histiocytic Sarcoma. The test will be optimized and refined with advanced research. For this your participation is essential.

NOTE: DNA extracted from your dog's sample may be used for research in canine genetics.